DandRX Shampoo + Conditioner
DANDRX is the first and only stem cell–powered, medicated anti-dandruff shampoo that contains 2% Pyrithione Zinc, which is double the active strength of most dandruff shampoos on the market, and stem cells to target even the most resistant dandruff.
With our 30-Day Flake-Free Guarantee, you’ll stay clear and confident—or your money back.
- 2X Strength of Regular Dandruff Shampoos
- The Only Stem Cell Dandruff Shampoo
- Fragrant Free For Sensitive Scalps
- Made by a Physician
DandRX is clinically proven to treat dandruff and promote a healthy, balanced scalp. DandRX helps soothe dryness and itchiness.
Wet your hair and scalp thoroughly, then apply a small amount of DandRX's dandruff shampoo directly to your scalp. Massage gently with your fingertips and let it sit for 2–3 minutes before rinsing well. Use 2–3 times per week, and follow with DandRX's conditioner on the lengths if needed. If irritation occurs, discontinue use and consult a doctor.
Shampoo: Active: 2% Pyrithione Zinc
, Inactive: Water (Aqua), Sodium C14-16 Olefin Sulfonate, Acrylates Copolymer, Cocamidopropyl Betaine, Cocamidopropylamine Oxide, Cocamide MEA, Methyl Gluceth-20, Sodium Hydroxide, Polyquaternium-7, Camellia Sinensis Leaf Extract, Malus Domestica Fruit Cell Culture Extract, Argania Spinosa Kernel Oil (Organic), Cocos Nucifera Oil (Organic), Propylene Glycol, Biotin, Hydrolyzed Keratin, Xanthan Gum, Sodium Benzoate, Disodium EDTA, Citric Acid, Panthenol, Ethylhexylglycerin, Phenoxyethanol.
Conditioner: Water (Aqua), Cetyl Alcohol, Hydrolyzed Wheat Protein, Trehalose, Aminoethyl Aminopropyl Polydimethylsiloxane, Hydrolyzed Keratin, Cetyl Trimethylammonium Chloride, Polydimethylsiloxane, Aloe Barbadensis Leaf Extract, Panthenol, Fragrance (Parfum).
Real People. Real Results.
Venessa R.
"If you're tired of dealing with dandruff and noting else has worked, I highly recommend giving dandrx a try. From the first wash, I felt a calming sensation on my scalp, and within 2 weeks of regular use, my flakes were significantly reduced. My scalp feels healthy and itch- free."
91%
said hair looked healthier and saw an improvement in dandruff.
Results from a double-blind, in-vivo clinical trial involving 40 subjects, 21-62 years old, over 150 days.
Science Behind The Formula
2% Pyrithione Zinc
Pyrithione Zinc is a clinically proven antifungal and antibacterial ingredient used to treat d... read more
Pyrithione Zinc is a clinically proven antifungal and antibacterial ingredient used to treat dandruff and seborrheic dermatitis. It works by targeting and reducing the overgrowth of Malassezia — a naturally occurring yeast on the scalp that causes flaking, itching, and irritation.
Most over-the-counter shampoos contain 1% Pyrithione Zinc, but a 2% concentration offers double the active strength, providing faster, more complete relief from stubborn dandruff. In addition to its antimicrobial benefits, it also helps soothe inflammation, calm scalp redness, and restore a healthy scalp barrier — all while being gentle enough for regular use.
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Stem Cells
Stem cells in hair care—particularly plant-derived stem cells—are advanced bioactive ingredien... read more
Stem cells in hair care—particularly plant-derived stem cells—are advanced bioactive ingredients known for their ability to revitalize, protect, and repair the scalp and hair follicles at a cellular level. In DandRx, these stem cells are used to promote a healthier scalp environment by delivering potent antioxidants and growth factors that support natural regeneration.
Unlike ordinary botanical extracts, plant stem cells contain unique compounds that encourage new cell turnover, help protect scalp cells from oxidative stress, and strengthen the hair’s natural barrier. This means less inflammation, reduced irritation, and improved scalp resilience—key factors in long-term dandruff control and overall scalp health.
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Cleanest Dandruff Shampoo Formula
While most anti-dandruff products rely on harsh detergents, artificial fragrance, and fillers,... read more
While most anti-dandruff products rely on harsh detergents, artificial fragrance, and fillers, our formula is clinically potent yet remarkably clean. Every ingredient serves a purpose — to soothe, treat, and restore scalp health without unnecessary additives.
We use 2% Pyrithione Zinc for proven antifungal efficacy, plant stem cells for cellular renewal, and botanical extracts to calm and nourish the scalp. DandRx is free from sulfates, parabens, silicones, and synthetic dyes, making it safe for daily use and all hair types.
read less
2% Pyrithione Zinc
Pyrithione Zinc is a clinically proven antifungal and antibacterial ingredient used to treat d... read more
Pyrithione Zinc is a clinically proven antifungal and antibacterial ingredient used to treat dandruff and seborrheic dermatitis. It works by targeting and reducing the overgrowth of Malassezia — a naturally occurring yeast on the scalp that causes flaking, itching, and irritation.
Most over-the-counter shampoos contain 1% Pyrithione Zinc, but a 2% concentration offers double the active strength, providing faster, more complete relief from stubborn dandruff. In addition to its antimicrobial benefits, it also helps soothe inflammation, calm scalp redness, and restore a healthy scalp barrier — all while being gentle enough for regular use.
read less
Stem Cells
Stem cells in hair care—particularly plant-derived stem cells—are advanced bioactive ingredien... read more
Stem cells in hair care—particularly plant-derived stem cells—are advanced bioactive ingredients known for their ability to revitalize, protect, and repair the scalp and hair follicles at a cellular level. In DandRx, these stem cells are used to promote a healthier scalp environment by delivering potent antioxidants and growth factors that support natural regeneration.
Unlike ordinary botanical extracts, plant stem cells contain unique compounds that encourage new cell turnover, help protect scalp cells from oxidative stress, and strengthen the hair’s natural barrier. This means less inflammation, reduced irritation, and improved scalp resilience—key factors in long-term dandruff control and overall scalp health.
read less
Cleanest Dandruff Shampoo Formula
While most anti-dandruff products rely on harsh detergents, artificial fragrance, and fillers,... read more
While most anti-dandruff products rely on harsh detergents, artificial fragrance, and fillers, our formula is clinically potent yet remarkably clean. Every ingredient serves a purpose — to soothe, treat, and restore scalp health without unnecessary additives.
We use 2% Pyrithione Zinc for proven antifungal efficacy, plant stem cells for cellular renewal, and botanical extracts to calm and nourish the scalp. DandRx is free from sulfates, parabens, silicones, and synthetic dyes, making it safe for daily use and all hair types.
read lessPurity That’d Make a Diamond Jealous
Fragrance Free
Double Anti-Fungal Strength
Safe For All Hair Types
Sulphate Free
Phthalate Free
Paraben Free
Our formula is completely sulfate-free, ensuring a gentle cleanse that won’t strip your scalp or hair of natural oils.
DandRx is proudly phthalate-free, meaning it’s made without harsh chemical plasticizers that can irritate the scalp or disrupt hormones.
We’ve eliminated parabens to keep our formula pure, safe, and non-irritating for even the most sensitive scalps. Instead, we use modern, clean preservatives that maintain product freshness without compromising your health.
Before & After DandRX
Based on a study of 50 users of DandRX.
Before
After
Before & After DandRX
Based on a study of 50 users of DandRX.
91 %
of participants noticed improvement with reducing of flakes.
95 %
of participants noticed improvement with itching symptoms.
85 %
of participants noticed improvement in dry scalp findings.
US vs Other Brands
We take pride in our uncompromising quality standards and using only clinically proven, dermatologist-trusted ingredients in every formulation.
Fragrant Free
Innovative Formula
Double Anti-Fungal Strength
Dermatologist Recommended
DandRX
Other Brands
Paraben Free
Phthalate Free
Sulphate Free
Physician Founded
Stem Cells
2% Pyrithione Zinc
Founded by a Physician, Backed by Science
As a physician, I’ve always believed that effective treatment should never come at the cost of your overall health. That’s why I created DandRx, a sulfate-free, physician-formulated dandruff shampoo designed with the core principle of "Do No Harm." Too many dandruff shampoos rely on harsh chemicals that strip the scalp of its natural balance, leading to irritation, dryness, and long-term damage. I wanted to change that. With DandRx, I combined clinically proven anti-dandruff ingredients with soothing botanicals and a clean, non-toxic formula to fight flakes without compromising scalp health.
Dr. Deepak Khanna D.O
Reviews
- AAngelaVerified ReviewerReviewingDandRX Shampoo + ConditionerI recommend this productRated 5 out of 5 starsworked for my daughter thx
My daughter is 12 years old and she been suffering with itching, drying and flaking on head for 3 months. I've tried many shampoo for her, like Dove, Pantene, Head&Shoulders, tea tree oil and many more. But nothing works, she kept scratching so much that it bleeds, and the worst part, her hair got so much flakes that it looks like lice eggs. I'm so thankful I was searching and came across this
- CYChris Y.ReviewingDandRX Shampoo + ConditionerI recommend this productRated 5 out of 5 starsFinally found a treatment that moisturizes and treats my dandruff
My 12-year-old son has autism, seborrheic dermatitis, and extremely sensitive skin, so hair washing can be a tough experience. Most salicylic acid shampoos irritate his scalp, and while Nizoral helps a bit, it’s never been quite enough.
This shampoo has been such a relief—it’s both gentle and effective. His scalp handled it really well, and I noticed an improvement right away.Thank you for creating something that truly works for sensitive skin!
- RRozayReviewingDandRX Shampoo + ConditionerI recommend this productRated 5 out of 5 starsUse it for my dreads, got rid of dry skin and dandruff
Great product for people with dreadlocks. My hair smells and feels lighter. I ACV wash my stuff as well 2 times a year, and cover it all the time but I still struggled with dryness and dandruff with fungal smell. This shampoo cured that in the first week. Having thick hair means you got to use more product unfortunately, the way to combat this is to section your hair so you can get the scalp and scrub with your fingernails in between the parts. For my texture you will run through the shampoo way faster. I suggest buying the combo
- JHJonah H.Verified ReviewerReviewingDandRX Shampoo + ConditionerI recommend this productRated 5 out of 5 starsgood
I have had flakes for many many years at least that I can remember. I've tried everything even the no poo method, selson blu, Neutrogena t/Sal dandruff shampoo, tea tree shampoo, headnshoulders, Washing everyday, washing every 4 days, oiling my scalp, Exploiting my scalp, Hair masks, Even homemade hairmasks. Nothing worked I have really dry scalp and my dandruff was The size of about around a nickel and I had given up Since nothing was working this shampoo was on my recommended Since my intention was to try the scalp spray That is what I looked for on google Since I wanted to give it one last try In trying to find something That would help me So i bought these together the scalps spray came first and it really helped to moisturize and I saw an immediate reduction in my flakes A couple of Days later the shampoo came and Usually after I come out of the shower my head will start to flake almost immediately but Right after the first use All of my dandruff was completely gone but These two together have been a match made in heaven for me I am happy to finally say I am completely dandruff free. I started with using the shampoo every other day when I wash my hair Then moved on to Twice a week then to once a week I now only use the shampoo once a month but I still spray my scalp after every wash with my scalp spray. I can now wear my hair down shake my hair and And run my fingers through my hair everything I could not do for a very long time I Ordered a second bottle but I still have…
- AKAndre K.ReviewingDandRX Shampoo + ConditionerI recommend this productRated 5 out of 5 starsThank you dandrx and Dr.Khanna
Gave this over 11 days before writing anything because I wanted to really see how it performed—and honestly, I’m blown away. I went in skeptical and even tried to push its limits… but it held up beautifully ❤️
With this, I made it all the way to the evening of day three before feeling the need to wash again. That’s huge for me. I pushed it on purpose, and my scalp still felt calm and happy. Massive thank you to Dr. Khanna —this is 100% a new staple in my hair care routine!