DandRX Shampoo + Conditioner

DandRX Shampoo + Conditioner

$29.99 $39.99
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DandRX Shampoo + Conditioner
DandRX Shampoo + Conditioner

DANDRX Shampoo + Conditioner

5.0
Rated 5.0 out of 5 stars
288 Reviews
$29.99 $39.99 SALE

The first and only stem cell-powered medicated anti-dandruff shampoo. Formulated with 2% Pyrithione Zinc - twice the active strength of regular dandruff shampoos - to eliminate flakes. In addition, stem cell technology and biotin helps support a healthier scalp and strengthen your hair.

DandRX comes with a 30-Day Flake-Free Guarantee so you’ll stay clear and confident— or your money back.
Benefits

DandRX is clinically proven to treat dandruff and promote a healthy, balanced scalp. DandRX helps soothe dryness and itchiness.
Ingredients

Shampoo: Active: 2% Pyrithione Zinc
, Inactive: Water (Aqua), Sodium C14-16 Olefin Sulfonate, Acrylates Copolymer, Cocamidopropyl Betaine, Cocamidopropylamine Oxide, Cocamide MEA, Methyl Gluceth-20, Sodium Hydroxide, Polyquaternium-7, Camellia Sinensis Leaf Extract, Malus Domestica Fruit Cell Culture Extract, Argania Spinosa Kernel Oil (Organic), Cocos Nucifera Oil (Organic), Propylene Glycol, Biotin, Hydrolyzed Keratin, Xanthan Gum, Sodium Benzoate, Disodium EDTA, Citric Acid, Panthenol, Ethylhexylglycerin, Phenoxyethanol.

Conditioner: Water (Aqua), Cetyl Alcohol, Hydrolyzed Wheat Protein, Trehalose, Aminoethyl Aminopropyl Polydimethylsiloxane, Hydrolyzed Keratin, Cetyl Trimethylammonium Chloride, Polydimethylsiloxane, Aloe Barbadensis Leaf Extract, Panthenol, Fragrance (Parfum).
Directions

Wet your hair and scalp thoroughly, then apply a small amount of DandRX's dandruff shampoo directly to your scalp. Massage gently with your fingertips and let it sit for 2–3 minutes before rinsing well. Use 2–3 times per week, and follow with DandRX's conditioner on the lengths if needed. If irritation occurs, discontinue use and consult a doctor.

As Seen on

This shampoo is effective for relieving my itchy scalp. It is not drying to my hair. There is no fragrance or any that lasts and competes.

Daniel R.

Out of desperation I went on the hunt...I read so many reviews and saw so much of the same that I'd already saw and researched. Then, I noticed a sleek black bottle, read the ingredients (2%!!), info and reviews and said...why not? Let me tell you...my scalp is delighted!

Emma L.

I was honestly surprised to see it work so quickly. Did not expect that!

Jared M.

I have been using this DANDRX shampoo for a month and it has solved my scalp problem. It solved it quickly, but I wanted to wait a while before recommending. DANDRX truly has no scent that I could detect. No allergic reaction for me. No dyes in it that I could see in the ingredient list. It lathers and cleans well.

Theo J.

I really like this shampoo. I got it for my itchy dry head and scalp. It has worked very well. The itching has been almost nonexistent since I started using this shampoo regularly

James T.

Ive had dry scalp, or fungus, or whatever on my scalp for as long as I can remember. Tee tree oil was the only thing that mildly helped but it stinks to high heaven. In my search for something else I came across DANDRX and decided to give it a try. Im glad I did because after a few weeks it cleared up the constant flakes that appeared all over my scalp.

Michael B.

SEEING IS BELIEVING

Real People. Real Results

BEFORE
AFTER

Venessa R.

"If you're tired of dealing with dandruff and noting else has worked, I highly recommend giving dandrx a try. From the first wash, I felt a calming sensation on my scalp, and within 2 weeks of regular use, my flakes were significantly reduced. My scalp feels healthy and itch free."

91%

said hair looked healthier and saw an improvement in dandruff.
Results from a double-blind, in-vivo clinical trial involving 40 subjects, 21-62 years old, over 150 days.

Physician Founded

As a physician, I’ve always believed that effective treatment should never come at the cost of your overall health. That’s why I created DandRx, a sulfate-free, physician-formulated anti-dandruff shampoo designed with the core principle of "Do No Harm." Too many dandruff shampoos rely on harsh chemicals that strip the scalp of its natural balance, leading to irritation, dryness, and long-term damage. I wanted to change that. With DandRx, I combined clinically proven anti-dandruff ingredients with soothing botanicals and a clean, non-toxic formula to fight flakes without compromising scalp health.

Flake Free or Your Money Back

That is how confident we are that DandRX will be your solution to fighting flakes. We put our money where our mouth is.

Meet The Ingredients

2% Pyrithione Zinc

Pyrithione Zinc is a clinically proven antifungal and antibacterial ingredient used to treat dandruff and seborrheic dermatitis. It works by targeting and reducing the overgrowth of Malassezia — a naturally occurring yeast on the scalp that causes flaking, itching, and irritation.

Anti-Fungal

Biotin

Biotin helps nourish and strengthen the hair, supporting a healthier-looking, fuller appearance. Added to shampoo, it helps give hair a stronger, smoother, more revitalized feel with regular use.

Nourish

Strengthen

Stem Cells

Stem cells in hair care, particularly plant-derived stem cells, are advanced bioactive ingredients known for their ability to revitalize, protect, and repair the scalp and hair follicles at a cellular level. 

Repair

2% Pyrithione Zinc

Pyrithione Zinc is a clinically proven antifungal and antibacterial ingredient used to treat dandruff and seborrheic dermatitis. It works by targeting and reducing the overgrowth of Malassezia — a naturally occurring yeast on the scalp that causes flaking, itching, and irritation.

Anti-Fungal

Biotin

Biotin helps nourish and strengthen the hair, supporting a healthier-looking, fuller appearance. Added to shampoo, it helps give hair a stronger, smoother, more revitalized feel with regular use.

Nourish

Strengthen

Stem Cells

Stem cells in hair care, particularly plant-derived stem cells, are advanced bioactive ingredients known for their ability to revitalize, protect, and repair the scalp and hair follicles at a cellular level. 

Repair

See The Difference

What's the difference between DandRX and other dandruff brands? Glad you asked.

Cleanest Formula + Fragrant Free

Includes Biotin + Stem Cells

Double Anti-Fungal Strength

Physician Made

DANDRX

Other Brands

Sulfate Free
Phthalate Free
Paraben Free
Physician Founded
Fragrant Free
2% Pyrithione Zinc

Frequently Asked Questions

What is Pyrithione Zinc?

Pyrithione Zinc is an antifungal ingredient that helps control dandruff by targeting the yeast that contributes to flaking, itching, and irritation.
Can dandruff lead to hair loss?

Yes, severe dandruff can cause inflammation and itching, leading to excessive scratching that weakens hair follicles and contributes to hair thinning or shedding.
What does DANDRX treat?

DandRx is designed to treat dandruff, dry scalp, flaking, itching, and irritation while promoting overall scalp health.
How long does it take for DANDRX to work?

Most users notice improvement within a few washes, but for best results, consistent use over 2-4 weeks is recommended.
How are you different from other brands?

DandRx is physician-formulated, sulfate-free, and made with clean, non-toxic ingredients—delivering powerful dandruff relief without harming your scalp or hair.
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288 reviews
  • A
    Angela
    Verified Reviewer
    Reviewing
    DandRX Shampoo + Conditioner
    I recommend this product
    Rated 5 out of 5 stars
    worked for my daughter thx

    My daughter is 12 years old and she been suffering with itching, drying and flaking on head for 3 months. I've tried many shampoo for her, like Dove, Pantene, Head&Shoulders, tea tree oil and many more. But nothing works, she kept scratching so much that it bleeds, and the worst part, her hair got so much flakes that it looks like lice eggs. I'm so thankful I was searching and came across this

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  • CY
    Chris Y.
    Reviewing
    DandRX Shampoo + Conditioner
    I recommend this product
    Rated 5 out of 5 stars
    Finally found a treatment that moisturizes and treats my dandruff

    My 12-year-old son has autism, seborrheic dermatitis, and extremely sensitive skin, so hair washing can be a tough experience. Most salicylic acid shampoos irritate his scalp, and while Nizoral helps a bit, it’s never been quite enough.

    This shampoo has been such a relief—it’s both gentle and effective. His scalp handled it really well, and I noticed an improvement right away.Thank you for creating something that truly works for sensitive skin!

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  • R
    Rozay
    Reviewing
    DandRX Shampoo + Conditioner
    I recommend this product
    Rated 5 out of 5 stars
    Use it for my dreads, got rid of dry skin and dandruff

    Great product for people with dreadlocks. My hair smells and feels lighter. I ACV wash my stuff as well 2 times a year, and cover it all the time but I still struggled with dryness and dandruff with fungal smell. This shampoo cured that in the first week. Having thick hair means you got to use more product unfortunately, the way to combat this is to section your hair so you can get the scalp and scrub with your fingernails in between the parts. For my texture you will run through the shampoo way faster. I suggest buying the combo

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  • JH
    Jonah H.
    Verified Reviewer
    Reviewing
    DandRX Shampoo + Conditioner
    I recommend this product
    Rated 5 out of 5 stars
    good

    I have had flakes for many many years at least that I can remember. I've tried everything even the no poo method, selson blu, Neutrogena t/Sal dandruff shampoo, tea tree shampoo, headnshoulders, Washing everyday, washing every 4 days, oiling my scalp, Exploiting my scalp, Hair masks, Even homemade hairmasks. Nothing worked I have really dry scalp and my dandruff was The size of about around a nickel and I had given up Since nothing was working this shampoo was on my recommended Since my intention was to try the scalp spray That is what I looked for on google Since I wanted to give it one last try In trying to find something That would help me So i bought these together the scalps spray came first and it really helped to moisturize and I saw an immediate reduction in my flakes A couple of Days later the shampoo came and Usually after I come out of the shower my head will start to flake almost immediately but Right after the first use All of my dandruff was completely gone but These two together have been a match made in heaven for me I am happy to finally say I am completely dandruff free. I started with using the shampoo every other day when I wash my hair Then moved on to Twice a week then to once a week I now only use the shampoo once a month but I still spray my scalp after every wash with my scalp spray. I can now wear my hair down shake my hair and And run my fingers through my hair everything I could not do for a very long time I Ordered a second bottle but I still have…

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  • AK
    Andre K.
    Reviewing
    DandRX Shampoo + Conditioner
    I recommend this product
    Rated 5 out of 5 stars
    Thank you dandrx and Dr.Khanna

    Gave this over 11 days before writing anything because I wanted to really see how it performed—and honestly, I’m blown away. I went in skeptical and even tried to push its limits… but it held up beautifully ❤️

    With this, I made it all the way to the evening of day three before feeling the need to wash again. That’s huge for me. I pushed it on purpose, and my scalp still felt calm and happy. Massive thank you to Dr. Khanna —this is 100% a new staple in my hair care routine!

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